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Potential Trulicity side effects include reactions listed and not listed on the label. The diabetes medication may cause common side effects like abdominal pain, diarrhea, nausea and vomiting. It may also cause severe conditions like Acute Kidney Injury (AKI), gastroparesis, pancreatitis and thyroid cancer.
Key takeaways about Trulicity side effects
- Trulicity is a medication used to control type 2 diabetes.
- People taking Trulicity have suffered severe harm from alleged side effects not described on the medication’s label.
- Lawsuits are being filed by patients who sustained thyroid cancer and other serious conditions as a result of Trulicity use.
What is Trulicity?
Trulicity is a drug used to treat type 2 diabetes. Trulicity uses the active ingredient dulaglutide (a GLP-1 receptor agonist) to control blood sugar levels when used once a week with proper diet and exercise.
The U.S. Food and Drug Administration (FDA) approved Trulicity in 2014 to treat adult patients with type 2 diabetes. Eli Lilly and Company currently manufactures the drug.
How does Trulicity work?
Trulicity works by stimulating the GLP-1 receptor in a person’s body. This prompts the body to release more insulin and slow digestion. Additionally, the drug prevents the body from releasing more sugar into the bloodstream. These efforts help the body control and maintain appropriate blood sugar levels.
Trulicity may also benefit patients who suffer from type 2 diabetes and issues with their heart or blood vessels. For some patients, Trulicity has shown to be effective in reducing the risk of death, heart attack or stroke.
What are the potential side effects of Trulicity?
Trulicity use may lead to both listed and unlisted side effects.
- Listed side effects are potential adverse reactions that pharmaceutical companies include on drug warning labels.
- Unlisted side effects are alleged reactions to the medication that are not disclosed in the product information.
Listed side effects of Trulicity
The warning label for Trulicity lists common side effects and more severe side effects that may result from the use of the medication.
The warning label for Trulicity label lists several common side effects, such as:
- Abdominal pain
- Diarrhea
- Nausea
- Reduced appetite
- Vomiting
Common Trulicity side effects can be temporary, sometimes lasting several days or weeks. If you experience longer-lasting side effects, you should consult your doctor as soon as possible.
The Trulicity label also warns of severe side effects that may affect some people. These effects include:
- Acute kidney injury (AKI): A sudden condition in which the kidneys cannot filter waste from the blood. AKI typically happens within a few hours or days.
- Diabetic retinopathy: Damage to the retina due to high blood sugar. Trulicity can cause diabetic retinopathy to get worse.
- Hypersensitivity reactions: Anaphylactic reactions and angioedema have occurred with Trulicity use. These reactions can lead to skin discoloration, pain, rash and swelling.
- Hypoglycemia: Low blood sugar that occurs when blood glucose drops below healthy levels. Trulicity may cause hypoglycemia, particularly when it is used with insulin or other medications that affect a patient’s insulin levels. In clinical studies, when Trulicity was used with insulin, 69% to 77% of the study participants developed hypoglycemia.
- Pancreatitis: Acute or chronic inflammation of the pancreas. According to the Trulicity label, pancreatitis was reported in clinical trials, with instructions to discontinue and not restart the medication if the condition develops.
- Severe gastrointestinal disease: Trulicity has been linked with serious gastrointestinal conditions.
- Thyroid C-cell tumors: Trulicity contains a boxed warning about thyroid cancer. The medication increased the risk of thyroid C-cell tumors in animals, but it is unknown whether this risk is increased in humans.
A boxed warning, also known as a black box warning, is an FDA safety alert included on a prescription’s label to emphasize its most serious risks.
If you believe you are experiencing any severe side effects from the use of Trulicity, seek medical advice immediately.
Unlisted side effects of Trulicity
People have reported unlisted side effects of Trulicity, meaning other side effects beyond those listed on the warning label. Some of the unlisted side effects of Trulicity include:
- Gallbladder issues: Short-term gallbladder conditions, including gallbladder inflammation (cholecystitis) and gallstones, have been reported by Trulicity users.
- Gastroparesis: A condition also known as delayed gastric emptying that slows or stops the movement of food from the stomach to the small intestine, even when no blockage in the stomach or intestines exists. Severe digestive issues, including gastroparesis, may be linked to Trulicity use.
- Hyperglycemia: High blood sugar may occur with Trulicity use. Symptoms include blurred vision, dry mouth, fatigue, increased frequency and amount of urination and trouble breathing.
Individuals who experience these or other unlisted side effects may be eligible for a Trulicity lawsuit.
Contact a Trulicity lawyer today
If you or a loved one experienced harmful side effects after taking Trulicity, you may be able to file a lawsuit against Eli Lilly, the maker of Trulicity. Call 1.800.768.4026 to contact attorneys Sara Couch and Jonathan Orent for more information or to discuss a potential Trulicity claim.
FAQs about Trulicity side effects
What are the worst side effects of Trulicity?
Trulicity has been associated with numerous severe and long-term side effects that are listed and unlisted, including:
- Acute Kidney Injury (AKI)
- Diabetic retinopathy complications
- Gastroparesis
- Hypersensitivity reactions
- Hypoglycemia
- Pancreatitis
- Thyroid C-cell tumors
Some conditions resulting from taking Trulicity, like gastroparesis, may be long-term. Certain long-term side effects of Trulicity may make a person eligible to file a Trulicity lawsuit.
How long do Trulicity side effects last?
Some Trulicity side effects may be temporary, lasting a few days or weeks, but others may be long-term. Abdominal pain, nausea and vomiting may be temporary, while some side effects, like kidney problems, are serious and may last longer.
How to deal with Trulicity side effects?
Some side effects may pass with time, but it’s important for people experiencing Truclicity-related long-term side effects to let their doctors know. Continue taking any prescribed medication until you speak with your doctor.
When should someone speak with a Trulicity lawyer?
Someone may consider speaking with a Trulicity lawyer if their doctor diagnoses them with a severe, unlisted side effect from using the drug. More than 1,500 patients harmed by GLP-1 RA drugs like Trulicity have filed diabetes lawsuits against Eli Lilly and other drug manufacturers.
Other GLP-1 medications involved in ongoing litigation include:
Our medical drug experience
Our medical attorneys have represented thousands of patients seriously hurt by dangerous over-the-counter and prescription medications like Trulicity and other medical products. If you believe a medication made you sick or harmed you, our attorneys have the resources needed to thoroughly investigate your potential claim. We can help you:
- Pinpoint potentially harmful medications
- Investigate whether the medication harmed you
- Assess whether Trulicity maker Eli Lilly complied with FDA regulations
- Determine the adequacy of Eli Lilly’s warning to you regarding potential side effects
- Consider other issues that might affect your lawsuit
Learn more about our law firm’s medical drug lawsuit experience here.
Do not stop taking a prescribed medication without first consulting with your doctor. Discontinuing a prescribed medication without your doctor's advice can result in injury or death. Trulicity, Mounjaro, Ozempic, Rybelsus and Wegovy remain approved by the U.S. Food and Drug Administration.
What is Trulicity?
What are the potential side effects of Trulicity?
FAQs about Trulicity side effects
Our medical drug experience
- Sources
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- Good RX. What is Trulicity (dulaglutide)?
- Healthline. Side Effects of Trulicity: What You Need to Know.
- Johns Hopkins Medicine. Pancreatitis.
- Mayo Clinic. Dulaglutide (Subcutaneous Route).
- Mayo Clinic. Hypoglycemia.
- Medical News Today. Trulicity (dulaglutide).
- Medical News Today. Trulicity side effects: What you should know.
- National Institute of Diabetes and Digestive and Kidney Diseases. Gastroparesis.
- National Eye Institute. Diabetic Retinopathy.
- National Kidney Foundation. Acute Kidney Injury (AKI).
- The University of Chicago Medicine. Liver Failure.
- U.S. Food and Drug Administration. HIGHLIGHTS OF PRESCRIBING INFORMATION: TRULICITY (dulaglutide) injection, for subcutaneous use.
- WebMD. Trulicity (dulaglutide) - Uses, Side Effects, and More.