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The Legal Team
Available by prescription and over-the-counter, proton pump inhibitors (PPIs) are a particularly strong class of medication used to treat gastroesophageal reflux disease (GERD), frequent heartburn, ulcers, esophagitis and other conditions arising from an over-production of stomach acid. However, PPIs have been linked to serious injuries including acute interstitial nephritis, chronic kidney disease, kidney failure and other serious, debilitating effects which may result in hospitalization or, tragically, even death.
Hundreds of lawsuits have been filed in the U.S. against PPI manufacturers, alleging effects caused by the drugs. Many plaintiffs claim that manufacturers continue to promote the use of the drugs without proper warning, and that had they known they risks they would not have taken PPIs.
In December 2014, the FDA required that warning labels be included on prescription PPIs to explain the risk of developing acute interstitial nephritis, a dangerous swelling of the kidneys that could lead to damage, “at any point during PPI therapy.” Additionally, a study of more than 250,000 patients published in January 2016 in the Journal of the American Medical Association (JAMA) found that those taking PPIs were 20 percent to 50 percent more likely to develop chronic kidney disease compared to those who were not on these medications.
Signs of kidney disease and failure may include:
The FDA first approved prescription PPIs in 1989 and they have since grown into the most widely used class of prescription and over-the-counter drugs in the country. PPIs have been marketed by several pharmaceutical companies over the years, including Abbott Laboratories, AstraZeneca, GlaxoSmithKline, Merck, Novartis, Procter & Gamble, Pfizer, Takeda, TAP Pharmaceutical and Wyeth.
Common brand-name PPI medications include:
Motley Rice medical attorneys have extensive experience litigating for patients who have suffered severe adverse effects and complications caused by dangerous prescription and over-the-counter drugs. We understand that as a patient or family member, your familiarity with medications you have been prescribed, and knowledge of potential risks, may be limited. Our attorneys have the resources needed to thoroughly investigate and identify potentially harmful products, medical causation, compliance with FDA regulations, alleged inadequacy of warnings, alleged wrongdoing and other factors that could affect your potential claim.
In addition to reviewing potential PPI cases, our attorneys have represented clients in several medical drug cases, including diabetes drugs Januvia®, Victoza®, Janumet®, and Byetta®; chemotherapy drug Taxotere®; gout medication Uloric®; MS medication Zinbryta®; and nausea medication Zofran®.
Do not stop taking a prescribed medication without first consulting with your doctor. Discontinuing a prescribed medication without your doctor's advice can result in injury or death.
Motley Rice LLC, a South Carolina Limited Liability Company, is engaged in the New Jersey practice of law through Motley Rice New Jersey LLC. Esther Berezofsky attorney responsible for New Jersey practice.