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Ozempic® Bowel & Intestinal Blockages

Ozempic use may lead to serious digestive issues, including bowel obstruction or ileus. Learn more about these conditions and when to seek medical and legal help.

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Case Overview

Taking Ozempic can cause severe gastrointestinal conditions such as ileus and bowel or intestinal obstructions. These medical conditions are serious and can become life threatening without proper treatment. Injured patients are filing lawsuits for the harms they experienced as a result of taking Ozempic.

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Key takeaways about Ozempic bowel obstruction

  • Ozempic use has been associated with reports of serious digestive conditions like ileus and bowel obstruction.
  • Common symptoms include bloating, constipation, severe abdominal pain, bloating, nausea and vomiting.
  • Seek medical attention if signs of bowel obstruction develop while using Ozempic.

Can Ozempic cause bowel obstruction?

Yes, Ozempic can cause bowel obstruction. In 2022, a study found Ozempic use increased the risk of intestinal obstruction. 

In September 2023, following numerous consumer reports, the FDA updated the Ozempic label to include a warning about ileus. Ileus and intestinal obstruction are sometimes used interchangeably to describe the same condition. However, they refer to different issues.

  • Intestinal obstruction: A physical blockage that prevents food or liquid from passing through the intestines.
  • Ileus: A functional issue where the intestines fail to move contents because of a lack of muscular activity. No physical blockage causes the ileus, but this mechanical issue may lead to one.

Both conditions can cause similar symptoms but require different approaches to diagnosis and treatment.

How does Ozempic cause bowel obstructions?

Ozempic may cause bowel obstructions by slowing down how quickly food leaves the stomach. This “delayed gastric emptying” keeps people fuller longer, balances blood sugar and helps with weight loss. When the stomach and intestines do not empty properly, blockages can occur.

What is Ozempic?

Ozempic (generic name semaglutide) is part of a class of medications known as GLP-1 agonists. These medications can help lower blood sugar and promote weight loss. Ozempic is approved by the U.S. Food and Drug Administration (FDA) to treat adults with type 2 diabetes. But it is not FDA-approved for weight loss.

Ozempic causes many side effects. These can include cyclical vomiting, nausea, gastroenteritis, gastroparesis, ileus and intestinal (bowel) obstruction. Many serious side effects are not disclosed on the Ozempic approval and warning label.

Symptoms of Ozempic intestinal blockage

The following symptoms are associated with intestinal blockage:

  • Abdominal swelling
  • Constipation
  • Cramping
  • Inability to pass gas
  • Loss of appetite
  • Severe abdominal pain

Many patients taking Ozempic have been hospitalized after experiencing the symptoms of bowel obstruction. Those taking Ozempic who experience constipation and other symptoms of intestinal blockage for several days or more should see a doctor as soon as possible.

Contact a GLP-1 RA attorney

If you or a loved one has suffered from a serious side effect that wasn’t on the label of a GLP-1 RA drug, you may be eligible to file a lawsuit.

You can also reach our team by calling 1.800.768.4026.

Intestinal blockages can have serious consequences

If nothing can pass through the intestine, surgery may be required to remove the blockage. If surgery is too risky, a metal stent might be inserted into the intestine to clear the obstruction. Once the patient’s condition stabilizes, they may still need surgery.

Without proper treatment, intestinal blockages can be dangerous and even deadly. ​​Semaglutide bowel obstructions can cause the intestine to tear, leaking bowel contents into other parts of the body. Intestinal blockage can lead to hospitalization and death. 

Patients who have experienced serious non-listed Ozempic side effects may be able to file a lawsuit. Ozempic lawsuits may help harmed patients receive compensation for their injuries.

Who can file a GLP-1 RA lawsuit? Individuals, or their loved ones, who suffered serious medical conditions after taking a branded GLP-1 RA drug prescribed by a doctor may be eligible to file a lawsuit. The condition must not have been on the drug’s warning label at the time of prescription.

Conditions that may be grounds for a lawsuit include:

  • Vision loss or changes
  • Ileus and intestinal blockages
  • Necrotizing pancreatitis
  • Pulmonary embolisms
  • Deep vein thrombosis (DVT)
  • Gastric distress including severe or permanent stomach paralysis
  • Surgical complications

Frequently asked questions about Ozempic and intestinal issues

Can GLP-1 cause bowel obstruction?

Yes, GLP-1 drugs may cause bowel obstruction. Ozempic slows the rate at which food leaves the stomach. When the stomach and intestines don’t empty properly, intestinal blockages may occur, leading to serious medical issues.

What are the warning signs of a bowel obstruction?

Signs of a bowel obstruction include abdominal swelling, constipation, cramping, inability to pass gas, loss of appetite and severe abdominal pain. If you’re taking a GLP-1 medication and experience any of these symptoms, contact your doctor immediately.

How can I prevent intestinal blockage on Ozempic?

Medical experts recommend Ozempic users focus on managing constipation to prevent intestinal blockages. This includes drinking water, increasing fiber consumption, staying active and taking stool softeners (if approved by your doctor).

Am I eligible for an Ozempic intestinal blockage lawsuit?

If you’re taking Ozempic and have suffered from severe side effects like an intestinal blockage, you may be eligible to file a lawsuit. An Ozempic lawyer can help determine your eligibility for this type of claim.

Our medical drug experience

Our medical attorneys have represented thousands of patients critically injured by prescription and over-the-counter drugs like Ozempic and Wegovy. We understand that as a patient or family member, your understanding of your or a loved one’s medications may be limited.

If you believe a medication made you ill or harmed you, our diabetes drug attorneys have the resources to thoroughly investigate and:

  • Identify potentially harmful medications
  • Examine how the medication harmed you
  • Evaluate the manufacturer’s compliance with FDA regulations
  • Determine whether the manufacturer warned you about potential side effects
  • Acknowledge other issues that could affect your potential claim

Read more on our medical drug litigation experience.


Do not stop taking a prescribed medication without first consulting with your doctor. Discontinuing a prescribed medication without your doctor’s advice can result in injury or death. Ozempic and Wegovy are still approved by the U.S. Food and Drug Administration.

Can Ozempic cause bowel obstruction?

Symptoms of Ozempic intestinal blockage

Frequently asked questions about Ozempic and intestinal issues

Our medical drug experience

About the Author

Sources
  1. CBS News. Ozempic side effects could lead to hospitalization — and doctors warn that long-term impacts remain unknown.
  2. Cleveland Clinic. GLP-1 Agonists.
  3. Faillie, JL, Yin, H, Yu, OHY, Herrero, A, Altwegg, R, Renoux, C, Azoulay, L. (2022). Incretin-Based Drugs and Risk of Intestinal Obstruction Among Patients With Type 2 Diabetes. Clin. Pharmacol. Ther., 111: 272282.
  4. GoodRx. Ozempic Can Cause Constipation: Here’s How to Get Relief.
  5. Healthline. Ozempic Label Updated to Include Blocked Intestines as Potential Side Effect.
  6. Mayo Clinic. Intestinal obstruction.
  7. The New York Times. We Know Where New Weight Loss Drugs Came From, but Not Why They Work.
  8. U.S. Food and Drug Administration. Drug Safety-related Labeling Changes (SrLC).
  9. U.S. Food and Drug Administration. FDA Adverse Event Reporting System (FAERS) Public Dashboard.
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